Gene
kiss1
- ID
- ZDB-GENE-080128-1
- Name
- KiSS-1 metastasis suppressor
- Symbol
- kiss1 Nomenclature History
- Previous Names
-
- kisspeptin (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Enables kisspeptin receptor binding activity. Acts upstream of or within neuronal action potential and regulation of fear response. Is expressed in several structures, including brain; digestive system; fat cell; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 32 figures from 21 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Lupton et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 13 with or without anosmia | Alliance | ?Hypogonadotropic hypogonadism 13 with or without anosmia | 614842 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR020207 | Metastasis-suppressor KiSS-1 |
Domain Details Per Protein
| Protein | Length | Metastasis-suppressor KiSS-1 |
|---|---|---|
|
UniProtKB:A8C5J1
|
116 |
Interactions and Pathways
No data available
Plasmids
No data available