Gene
recql5
- ID
- ZDB-GENE-071214-1
- Name
- RecQ helicase-like 5
- Symbol
- recql5 Nomenclature History
- Previous Names
-
- recql5l
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have 3'-5' DNA helicase activity and four-way junction helicase activity. Involved in negative regulation of mitotic recombination. Predicted to localize to chromosome; cytoplasm; and nucleus. Is expressed in several structures, including otic vesicle; pericardial region; presumptive neural retina; retina; and ventricular system. Orthologous to human RECQL5 (RecQ like helicase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Xie et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR010716 | RecQ helicase-like 5 |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR013257 | Set2 Rpb1 interacting domain |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR032284 | ATP-dependent DNA helicase RecQ, zinc-binding domain |
| Family | IPR004589 | DNA helicase, ATP-dependent, RecQ type |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | ATP-dependent DNA helicase RecQ, zinc-binding domain | DEAD/DEAH box helicase domain | DNA helicase, ATP-dependent, RecQ type | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | RecQ helicase-like 5 | Set2 Rpb1 interacting domain |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:X1WCM8
|
933 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
recql5-201
(1)
|
Ensembl | 3,085 nt | ||
| mRNA |
recql5-202
(1)
|
Ensembl | 2,628 nt |
Interactions and Pathways
No data available
Plasmids
No data available