Gene

atg12

ID
ZDB-GENE-071205-7
Name
ATG12 autophagy related 12 homolog (S. cerevisiae)
Symbol
atg12 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to be involved in several processes, including C-terminal protein lipidation; autophagosome assembly; and autophagy of mitochondrion. Predicted to localize to Atg12-Atg5-Atg16 complex and phagophore assembly site membrane. Is expressed in brain; liver; and muscle. Orthologous to human ATG12 (autophagy related 12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Lu et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
ecn3Allele with one deletionUnknownUnknownCRISPR
la019561TgTransgenic insertionUnknownUnknownDNA
la019562TgTransgenic insertionUnknownUnknownDNA
sa31002Allele with one point mutationUnknownPremature StopENU
sa42684Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-atg12 (2)
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Human Disease
Associated With atg12 Human Ortholog
No data available
Associated With atg12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR007242 Ubiquitin-like protein Atg12
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
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Domain Details Per Protein
Protein Length Ubiquitin-like domain superfamily Ubiquitin-like protein Atg12
UniProtKB:F5ATB4 120
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 16
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA atg12-201 (1) Ensembl 584 nt
mRNA atg12-202 (1) Ensembl 668 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-149K23ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanATG125
Amino acid sequence comparison (1)
Citations
1 - 10 of 26
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