Gene
nod1
- ID
- ZDB-GENE-071116-9
- Name
- nucleotide-binding oligomerization domain containing 1
- Symbol
- nod1 Nomenclature History
- Previous Names
-
- NLR-A1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have CARD domain binding activity and oligopeptide binding activity. Involved in defense response to bacterium and hatching behavior. Human ortholog(s) of this gene implicated in asthma. Is expressed in brain; digestive system; gill; pleuroperitoneal region; and unfertilized egg. Orthologous to human NOD1 (nucleotide binding oligomerization domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001315 | CARD domain |
| Domain | IPR007111 | NACHT nucleoside triphosphatase |
| Domain | IPR041075 | NOD2, winged helix domain |
| Domain | IPR041267 | NACHT, LRR and PYD domains-containing protein, helical domain HD2 |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
Domain Details Per Protein
| Protein | Length | CARD domain | Death-like domain superfamily | Leucine-rich repeat | Leucine-rich repeat domain superfamily | NACHT, LRR and PYD domains-containing protein, helical domain HD2 | NACHT nucleoside triphosphatase | NOD2, winged helix domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1RMD1
|
940 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance