Gene
gfpt2
- ID
- ZDB-GENE-071113-1
- Name
- glutamine-fructose-6-phosphate transaminase 2
- Symbol
- gfpt2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in UDP-N-acetylglucosamine metabolic process; fructose 6-phosphate metabolic process; and protein N-linked glycosylation. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GFPT2 (glutamine-fructose-6-phosphate transaminase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001347 | SIS domain |
Domain | IPR017932 | Glutamine amidotransferase type 2 domain |
Domain | IPR035466 | GlmS/AgaS, SIS domain 1 |
Domain | IPR035490 | GlmS/FrlB, SIS domain 2 |
Domain | IPR047084 | Glucosamine-fructose-6-phosphate aminotransferase, isomerising, N-terminal domain |
Family | IPR005855 | Glucosamine-fructose-6-phosphate aminotransferase, isomerising |
Homologous_superfamily | IPR029055 | Nucleophile aminohydrolases, N-terminal |
Homologous_superfamily | IPR046348 | SIS domain superfamily |
Domain Details Per Protein
Protein | Length | GlmS/AgaS, SIS domain 1 | GlmS/FrlB, SIS domain 2 | Glucosamine-fructose-6-phosphate aminotransferase, isomerising | Glucosamine-fructose-6-phosphate aminotransferase, isomerising, N-terminal domain | Glutamine amidotransferase type 2 domain | Nucleophile aminohydrolases, N-terminal | SIS domain | SIS domain superfamily |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q3S343
|
681 |
Interactions and Pathways
No data available
Plasmids
No data available