Gene

gfpt2

ID

ZDB-GENE-071113-1

Name

glutamine-fructose-6-phosphate transaminase 2

Symbol

gfpt2 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in UDP-N-acetylglucosamine metabolic process; fructose 6-phosphate metabolic process; and protein N-linked glycosylation. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GFPT2 (glutamine-fructose-6-phosphate transaminase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gfpt2 Human Ortholog

No data available

Associated With gfpt2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001347	SIS domain
Domain	IPR017932	Glutamine amidotransferase type 2 domain
Domain	IPR035466	GlmS/AgaS, SIS domain 1
Domain	IPR035490	GlmS/FrlB, SIS domain 2
Domain	IPR047084	Glucosamine-fructose-6-phosphate aminotransferase, isomerising, N-terminal domain
Family	IPR005855	Glucosamine-fructose-6-phosphate aminotransferase, isomerising
Homologous_superfamily	IPR029055	Nucleophile aminohydrolases, N-terminal
Homologous_superfamily	IPR046348	SIS domain superfamily