Gene

agla

ID

ZDB-GENE-071004-6

Name

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase a

Symbol

agla Nomenclature History

Previous Names

agl
si:ch211-153l6.1

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have 4-alpha-glucanotransferase activity and amylo-alpha-1,6-glucosidase activity. Predicted to be involved in glycogen catabolic process. Human ortholog(s) of this gene implicated in glycogen storage disease III. Orthologous to human AGL (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With agla Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
glycogen storage disease III	Alliance	Glycogen storage disease IIIa	232400
glycogen storage disease III	Alliance	Glycogen storage disease IIIb	232400

Associated With agla Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR029436	Eukaryotic glycogen debranching enzyme, N-terminal domain
Domain	IPR032788	Glycogen debranching enzyme, central domain
Domain	IPR032790	Glycogen debranching enzyme, C-terminal
Domain	IPR032792	Glycogen debranching enzyme, glucanotransferase domain
Family	IPR006421	Glycogen debranching enzyme, metazoa
Family	IPR010401	Glycogen debranching enzyme
Homologous_superfamily	IPR008928	Six-hairpin glycosidase superfamily
Homologous_superfamily	IPR017853	Glycoside hydrolase superfamily