Gene
rnf34b
- ID
- ZDB-GENE-071004-31
- Name
- ring finger protein 34b
- Symbol
- rnf34b Nomenclature History
- Previous Names
-
- zgc:171755
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol and nuclear speck. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human RNF34 (ring finger protein 34).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR049320 | E3 ubiquitin-protein ligase CARP1/2, FYVE/PHD zinc finger |
| Domain | IPR049323 | E3 ubiquitin-protein ligase CARP1, FYVE/PHD zinc finger |
| Domain | IPR055111 | E3 ubiquitin-protein ligase rififylin, HeH domain |
| Family | IPR051728 | RING-FYVE domain-containing E3 ubiquitin-protein ligase |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036361 | SAP domain superfamily |
Domain Details Per Protein
| Protein | Length | E3 ubiquitin-protein ligase CARP1/2, FYVE/PHD zinc finger | E3 ubiquitin-protein ligase CARP1, FYVE/PHD zinc finger | E3 ubiquitin-protein ligase rififylin, HeH domain | RING-FYVE domain-containing E3 ubiquitin-protein ligase | SAP domain superfamily | Zinc finger, FYVE/PHD-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A7MBY3
|
377 | ||||||||
|
UniProtKB:A0A8M2B9I4
|
398 | ||||||||
|
UniProtKB:F1RCH2
|
384 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rnf34b-201
(1)
|
Ensembl | 1,575 nt | ||
| mRNA |
rnf34b-202
(1)
|
Ensembl | 1,377 nt |
Interactions and Pathways
No data available
Plasmids
No data available