Gene
otulinb
- ID
- ZDB-GENE-070912-627
- Name
- OTU deubiquitinase with linear linkage specificity b
- Symbol
- otulinb Nomenclature History
- Previous Names
-
- fam105bb
- si:dkeyp-106c5.3
- wu:fc69a03
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in protein linear deubiquitination. Predicted to colocalize with LUBAC complex. Human ortholog(s) of this gene implicated in otulipenia. Orthologous to several human genes including OTULIN (OTU deubiquitinase with linear linkage specificity).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144154 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| otulipenia | Alliance | Autoinflammation, panniculitis, and dermatosis syndrome | 617099 |
| {Immunodeficiency 107, susceptibility to invasive staphylococcus aureus infection} | 619986 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | FAM105 | Inactive ubiquitin thioesterase OTULINL |
|---|---|---|---|
|
UniProtKB:A0A8M3B0B6
|
349 | ||
|
UniProtKB:A0A8M2BAN8
|
409 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
otulinb-203
(1)
|
Ensembl | 661 nt | ||
| mRNA |
otulinb-204
(1)
|
Ensembl | 906 nt | ||
| mRNA |
otulinb-206
(1)
|
Ensembl | 1,761 nt | ||
| ncRNA |
otulinb-003
(1)
|
Ensembl | 817 nt | ||
| ncRNA |
otulinb-004
(1)
|
Ensembl | 904 nt | ||
| ncRNA |
otulinb-006
(1)
|
Ensembl | 764 nt |
Interactions and Pathways
No data available
Plasmids
No data available