Gene
otc
- ID
- ZDB-GENE-070912-422
- Name
- ornithine transcarbamylase
- Symbol
- otc Nomenclature History
- Previous Names
-
- si:dkey-19h21.3
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have ornithine carbamoyltransferase activity. Predicted to be involved in arginine biosynthetic process via ornithine and citrulline biosynthetic process. Predicted to localize to mitochondrion. Is expressed in ball; brain; liver; and muscle. Human ortholog(s) of this gene implicated in ornithine carbamoyltransferase deficiency. Orthologous to human OTC (ornithine carbamoyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
ornithine carbamoyltransferase deficiency | Alliance | Ornithine transcarbamylase deficiency | 311250 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR006131 | Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain |
Domain | IPR006132 | Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding |
Family | IPR002292 | Ornithine/putrescine carbamoyltransferase |
Family | IPR006130 | Aspartate/ornithine carbamoyltransferase |
Homologous_superfamily | IPR036901 | Aspartate/ornithine carbamoyltransferase superfamily |
Domain Details Per Protein
Protein | Length | Aspartate/ornithine carbamoyltransferase | Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain | Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding | Aspartate/ornithine carbamoyltransferase superfamily | Ornithine/putrescine carbamoyltransferase |
---|---|---|---|---|---|---|
UniProtKB:E9QHD9
|
352 |
Interactions and Pathways
No data available
Plasmids
No data available