Gene

myo10

ID

ZDB-GENE-070912-277

Name

myosin X

Symbol

myo10 Nomenclature History

Previous Names

myo10b (1)
myo10l2
si:ch211-283p23.2

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; actin binding activity; and motor activity. Predicted to be involved in signal transduction. Predicted to localize to myosin complex. Is expressed in midbrain hindbrain boundary; otic vesicle; and rhombomere. Orthologous to human MYO10 (myosin X).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Sittaramane et al., 2008

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With myo10 Human Ortholog

No data available

Associated With myo10 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR000048	IQ motif, EF-hand binding site
Domain	IPR000159	Ras-associating domain
Domain	IPR000299	FERM domain
Domain	IPR000857	MyTH4 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR019748	FERM central domain
Domain	IPR019749	Band 4.1 domain
Domain	IPR031971	Unconventional myosin-X, coiled coil domain
Domain	IPR036124	Class X myosin, motor domain
Domain	IPR040640	Myosin X, N-terminal SH3 domain
Domain	IPR041797	Myosin X, FERM domain C-lobe
Family	IPR051724	Actin-based Motor Myosin
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR014352	FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR035963	FERM superfamily, second domain
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily
Homologous_superfamily	IPR038185	MyTH4 domain superfamily

Domain Details Per Protein

Protein	Length	Actin-based Motor Myosin	Band 4.1 domain	Class X myosin, motor domain	FERM/acyl-CoA-binding protein superfamily	FERM central domain	FERM domain	FERM superfamily, second domain	IQ motif, EF-hand binding site	Kinesin motor domain superfamily	Myosin X, FERM domain C-lobe	Myosin X, N-terminal SH3 domain	MyTH4 domain	MyTH4 domain superfamily	PH-like domain superfamily	Pleckstrin homology domain	P-loop containing nucleoside triphosphate hydrolase	Ras-associating domain	Unconventional myosin-X, coiled coil domain
UniProtKB:A0A8M9P844 InterPro	1425
UniProtKB:A0A8M6Z236 InterPro	1425
UniProtKB:A0A8M9PXE2 InterPro	2069
UniProtKB:B0S541 InterPro	2069
UniProtKB:A0A8M3B0G0 InterPro	2013

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	myo10-202 (1) Ensembl	Ensembl	530 nt	Select Tool
mRNA	myo10-203 (1) Ensembl	Ensembl	6,350 nt	Select Tool
mRNA	myo10-204 (1) Ensembl	Ensembl	3,663 nt	Select Tool ZFIN BLAST
mRNA	myo10-205 (1) Ensembl	Ensembl	1,126 nt	Select Tool ZFIN BLAST
ncRNA	myo10-003 (1) Ensembl	Ensembl	667 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations