Gene
cd28
- ID
- ZDB-GENE-070912-128
- Name
- CD28 molecule
- Symbol
- cd28 Nomenclature History
- Previous Names
-
- ctla4 (1)
- si:ch211-160b7.1
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to be involved in regulation of T cell proliferation. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in multiple sclerosis and type 1 diabetes mellitus. Orthologous to human CD28 (CD28 molecule).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Immunodeficiency 123 with HPV-related verrucosis | 620901 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytotoxic T-lymphocyte protein 4/CD28 | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin V-set domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BEX8
|
209 |
Interactions and Pathways
No data available
Plasmids
No data available