Gene

il10ra

ID

ZDB-GENE-070905-4

Name

interleukin 10 receptor, alpha

Symbol

il10ra Nomenclature History

Previous Names

IL10R1 (1)
crfb7 (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Exhibits cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 28. Is expressed in gill; heart; liver; muscle; and pleuroperitoneal region. Orthologous to human IL10RA (interleukin 10 receptor subunit alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Sunarto et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With il10ra Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
inflammatory bowel disease 28	Alliance	Inflammatory bowel disease 28, early onset, autosomal recessive	613148

Associated With il10ra Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003961	Fibronectin type III
Domain	IPR015373	Interferon/interleukin receptor domain
Family	IPR050650	Type II Cytokine and Tissue Factor Receptors
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily