Gene
crfb2
- ID
- ZDB-GENE-070905-2
- Name
- cytokine receptor family member b2
- Symbol
- crfb2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Exhibits interferon receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in hepatitis B and primary immunodeficiency disease. Orthologous to human IFNAR2 (interferon alpha and beta receptor subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR015373 | Interferon/interleukin receptor domain |
| Family | IPR050650 | Type II Cytokine and Tissue Factor Receptors |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Interferon/interleukin receptor domain | Type II Cytokine and Tissue Factor Receptors |
|---|---|---|---|---|---|---|
|
UniProtKB:B0UXH1
|
469 | |||||
|
UniProtKB:A0A8M2BFF0
|
474 |
Interactions and Pathways
No data available
Plasmids
No data available