Gene

suox

ID

ZDB-GENE-070718-3

Name

sulfite oxidase

Symbol

suox Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have heme binding activity; molybdopterin cofactor binding activity; and sulfite oxidase activity. Predicted to be involved in sulfur compound metabolic process. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in inherited metabolic disorder and isolated sulfite oxidase deficiency. Orthologous to human SUOX (sulfite oxidase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With suox Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
isolated sulfite oxidase deficiency	Alliance	Sulfite oxidase deficiency	272300

Associated With suox Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018506	Cytochrome b5, heme-binding site
Domain	IPR000572	Oxidoreductase, molybdopterin-binding domain
Domain	IPR001199	Cytochrome b5-like heme/steroid binding domain
Domain	IPR005066	Moybdenum cofactor oxidoreductase, dimerisation
Family	IPR008335	Eukaryotic molybdopterin oxidoreductase
Homologous_superfamily	IPR014756	Immunoglobulin E-set
Homologous_superfamily	IPR036374	Oxidoreductase, molybdopterin-binding domain superfamily
Homologous_superfamily	IPR036400	Cytochrome b5-like heme/steroid binding domain superfamily