ZFIN is now using GRCz12tu for Genomic Data
Gene
dagla
- ID
- ZDB-GENE-070619-1
- Name
- diacylglycerol lipase, alpha
- Symbol
- dagla Nomenclature History
- Previous Names
-
- nsddr (1)
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables lipoprotein lipase activity. Acts upstream of or within several processes, including endocannabinoid signaling pathway; optokinetic behavior; and swimming behavior. Predicted to be located in dendritic spine membrane; early endosome membrane; and postsynaptic density membrane. Predicted to be active in dendrite membrane and postsynaptic membrane. Is expressed in brain and cranial ganglion. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human DAGLA (diacylglycerol lipase alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Martella et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neuroocular syndrome 2, paroxysmal type | 168885 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/Beta hydrolase fold | Diacylglycerol Lipase-Related | Fungal lipase-type domain |
|---|---|---|---|---|---|
| UniProtKB:A0A8N7T821 | InterPro | 1051 | |||
| UniProtKB:A0A8M3BAT1 | InterPro | 906 | |||
| UniProtKB:E7F0B3 | InterPro | 1051 | |||
| UniProtKB:A0AB32TZ29 | InterPro | 906 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance