ZFIN ID: ZDB-GENE-070607-1
Gene Name: caspase 3, apoptosis-related cysteine peptidase b
Gene Symbol: casp3b
Previous Names: casp3l, caspase-3b (1)
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 3 from López-Muñoz et al., 2009
MUTANTS AND TARGETED KNOCKDOWNS

Allele Type Mutagen Suppliers
sa15886 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa22414 Point Mutation ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH casp3b HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process apoptotic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function cysteine-type endopeptidase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001309 (1)
  • InterPro:IPR002138 (1)
  • InterPro:IPR011600 (1)
  • InterPro:IPR015470 (1)
  • InterPro:IPR015917 (1)
  • InterPro:IPR016129 (1)
  • InterPro:IPR029030 (1)
  • PROSITE:PS01122 (1)
  • PROSITE:PS50207 (1)
  • PROSITE:PS50208 (1)
  • Pfam:PF00656 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA casp3b-001 (1) 5614
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM casp3b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    casp3b Contained in: [BAC] CH73-225I24 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001048066 (1) 858 bp
    Genomic GenBank:CU638740 (1) 57008 bp
    Select Tool
    Polypeptide UniProtKB:F1Q7K7 (1) 285 aa
    Sequence Clusters UniGene:94264 (1)
    Sequence Information (all 14)
    OTHER casp3b GENE PAGES
  • Gene:566604 (1)
  • VEGA:OTTDARG00000034567 (1)
  • Ensembl(Zv9):ENSDARG00000055045 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish casp3b 14  
    Human CASP3 4 (4q34)
  • OMIM:600636
  • Gene:836
  • Mouse Casp3 8 ( 26.39 cM)
  • MGI:107739
  • Gene:12367
  • Orthology Details
    CITATIONS (16)