Gene

cdk5rap1

ID

ZDB-GENE-070424-90

Name

CDK5 regulatory subunit associated protein 1

Symbol

cdk5rap1 Nomenclature History

Previous Names

zgc:162738

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to enable N6-isopentenyladenosine methylthiotransferase activity. Predicted to be involved in mitochondrial tRNA modification. Predicted to act upstream of or within tRNA modification. Predicted to be active in cytosol and mitochondrion. Orthologous to human CDK5RAP1 (CDK5 regulatory subunit associated protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cdk5rap1 Human Ortholog

No data available

Associated With cdk5rap1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020612	Methylthiotransferase, conserved site
Domain	IPR002792	TRAM domain
Domain	IPR006638	Elp3/MiaA/NifB-like, radical SAM core domain
Domain	IPR007197	Radical SAM
Domain	IPR013848	Methylthiotransferase, N-terminal
Family	IPR005839	Methylthiotransferase
Family	IPR006463	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB
Homologous_superfamily	IPR023404	Radical SAM, alpha/beta horseshoe
Homologous_superfamily	IPR038135	Methylthiotransferase, N-terminal domain superfamily