Gene

dph7

ID

ZDB-GENE-070410-57

Name

diphthamide biosynthesis 7

Symbol

dph7 Nomenclature History

Previous Names

wdr85
zgc:162277

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable diphthine methylesterase activity. Predicted to be involved in protein histidyl modification to diphthamide. Predicted to act upstream of or within methylation. Predicted to be active in cytoplasm. Orthologous to human DPH7 (diphthamide biosynthesis 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dph7 Human Ortholog

No data available

Associated With dph7 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR052415	Diphthine methyltransferase
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	Diphthine methyltransferase	WD40 repeat	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M3ASB0 InterPro	337
UniProtKB:A0A8M2BCI9 InterPro	442
UniProtKB:A0A8M9PKE8 InterPro	442
UniProtKB:A0A8M9PXX2 InterPro	337
UniProtKB:A3KNN6 InterPro	443