Gene
nme9
- ID
- ZDB-GENE-070410-39
- Name
- NME/NM23 family member 9
- Symbol
- nme9 Nomenclature History
- Previous Names
-
- nme8
- NM23-Z8 (1)
- txndc3
- txndc6
- zgc:162216
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable nucleoside diphosphate kinase activity. Predicted to act upstream of or within nucleotide metabolic process. Is expressed in male organism. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 6. Orthologous to several human genes including NME9 (NME/NM23 family member 9).
- Genome Resources
- Note
-
Desvignes et al. (2008) originally identified this gene as nme8, an ortholog to mammalian NME8, based, in part, on the mis-identified X. tropicalis gene/protein NP_001121456. Updated genome information indicates that nme8 was lost in zebrafish (and some other teleosts), suggesting this gene is actually orthologous to mammalian NME9
- Comparative Information
-
- All Expression Data
- 1 figure from Desvignes et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017937 | Thioredoxin, conserved site |
| Domain | IPR013766 | Thioredoxin domain |
| Domain | IPR034907 | Nucleoside diphosphate kinase-like domain |
| Family | IPR001564 | Nucleoside diphosphate kinase |
| Family | IPR051766 | Thioredoxin domain-containing protein |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
| Homologous_superfamily | IPR036850 | Nucleoside diphosphate kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Nucleoside diphosphate kinase | Nucleoside diphosphate kinase-like domain | Nucleoside diphosphate kinase-like domain superfamily | Thioredoxin, conserved site | Thioredoxin domain | Thioredoxin domain-containing protein | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QAK2
|
661 | |||||||
|
UniProtKB:A0A8M9Q4G2
|
665 | |||||||
|
UniProtKB:A0A8M9QJH0
|
660 | |||||||
|
UniProtKB:A4IG45
|
531 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available