Gene
drosha
- ID
- ZDB-GENE-070209-23
- Name
- drosha ribonuclease III
- Symbol
- drosha Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable ribonuclease III activity. Acts upstream of or within with a positive effect on primary miRNA processing. Acts upstream of or within angiogenesis. Predicted to be part of microprocessor complex. Predicted to be active in nucleus. Orthologous to human DROSHA (drosha ribonuclease III).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7150667 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Jiang et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000999 | Ribonuclease III domain |
| Domain | IPR014720 | Double-stranded RNA-binding domain |
| Domain | IPR044442 | RNase III, double-stranded RNA binding domain, animal |
| Family | IPR011907 | Ribonuclease III |
| Homologous_superfamily | IPR036389 | Ribonuclease III, endonuclease domain superfamily |
Domain Details Per Protein
| Protein | Length | Double-stranded RNA-binding domain | Ribonuclease III | Ribonuclease III domain | Ribonuclease III, endonuclease domain superfamily | RNase III, double-stranded RNA binding domain, animal |
|---|---|---|---|---|---|---|
|
UniProtKB:A2RV16
|
1289 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
drosha-203
(1)
|
Ensembl | 5,132 nt | ||
| mRNA |
rnasen-201
(1)
|
Ensembl | 4,230 nt | ||
| ncRNA |
rnasen-002
(1)
|
Ensembl | 711 nt |
Interactions and Pathways
No data available
Plasmids