Gene

nrxn3a

ID

ZDB-GENE-070206-9

Name

neurexin 3a

Symbol

nrxn3a Nomenclature History

Previous Names

nrxn3aa
nrxn3ab
im:7144250
wu:fj54c11

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable metal ion binding activity. Predicted to act upstream of or within angiogenesis and cell adhesion. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in alcohol dependence and nicotine dependence. Orthologous to human NRXN3 (neurexin 3).

Genome Resources

Note

nrxn3a has two isoforms, alpha (2 forms DQ641432 and DQ641433) and beta (DQ641434)

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7144250 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nrxn3a Human Ortholog

No data available

Associated With nrxn3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain
Domain	IPR001791	Laminin G domain
Domain	IPR003585	Neurexin/syndecan/glycophorin C
Domain	IPR027789	Syndecan/Neurexin domain
Family	IPR050372	Neurexin-related cell adhesion and synaptic protein
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily

Domain Details Per Protein

Protein	Length	Concanavalin A-like lectin/glucanase domain superfamily	EGF-like domain	Laminin G domain	Neurexin-related cell adhesion and synaptic protein	Neurexin/syndecan/glycophorin C	Syndecan/Neurexin domain
UniProtKB:A0A8M9PKU0 InterPro	1464
UniProtKB:A0A8M9PEA6 InterPro	1681
UniProtKB:A0A8M9P901 InterPro	464
UniProtKB:A0A8M9PEB2 InterPro	1470
UniProtKB:A1XQY0 InterPro	672
UniProtKB:A0A8M9P8Z3 InterPro	1686
UniProtKB:A0A8M9P070 InterPro	1687
UniProtKB:A0A8M9PNT7 InterPro	1673
UniProtKB:A0A8M9P072 InterPro	1664
UniProtKB:A1XQX8 InterPro	1697
UniProtKB:A0A8M9PKT1 InterPro	1692
UniProtKB:A0A8M9P074 InterPro	1462
UniProtKB:A0A8M9P8Z6 InterPro	1473
UniProtKB:A0A8M9PKT6 InterPro	1672

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	nrxn3a-204 (1) Ensembl	Ensembl	2,987 nt	Select Tool ZFIN BLAST
mRNA	nrxn3a-201 (1) Ensembl	Ensembl	3,623 nt	Select Tool ZFIN BLAST
mRNA	nrxn3a-202 (1) Ensembl	Ensembl	2,099 nt	Select Tool ZFIN BLAST
mRNA	nrxn3a-203 (1) Ensembl	Ensembl	2,408 nt	Select Tool ZFIN BLAST
mRNA	nrxn3a-208 (1) Ensembl	Ensembl	4,008 nt	Select Tool ZFIN BLAST
ncRNA	nrxn3a-004 (1) Ensembl	Ensembl	788 nt	Select Tool ZFIN BLAST
ncRNA	nrxn3a-005 (1) Ensembl	Ensembl	776 nt	Select Tool ZFIN BLAST
ncRNA	nrxn3a-006 (1) Ensembl	Ensembl	437 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations