Gene
bbc3
- ID
- ZDB-GENE-070119-4
- Name
- BCL2 binding component 3
- Symbol
- bbc3 Nomenclature History
- Previous Names
-
- Puma (1)
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Involved in cellular response to ionizing radiation; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to localize to mitochondrion. Is expressed in several structures, including central nervous system; head; heart; male organism; and pleuroperitoneal region. Orthologous to human BBC3 (BCL2 binding component 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 56 figures from 46 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR031661 | Bcl-2-binding component 3 |
Domain Details Per Protein
| Protein | Length | Bcl-2-binding component 3 |
|---|---|---|
|
UniProtKB:F1QKA1
|
181 | |
|
UniProtKB:Q0GKC9
|
181 |
Interactions and Pathways
No data available
Plasmids