Gene

git2b

ID

ZDB-GENE-070112-2192

Name

G protein-coupled receptor kinase interacting ArfGAP 2b

Symbol

git2b Nomenclature History

Previous Names

zgc:158416 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have GTPase activator activity and metal ion binding activity. Orthologous to human GIT2 (GIT ArfGAP 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Yu et al., 2011

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With git2b Human Ortholog

No data available

Associated With git2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001164	Arf GTPase activating protein
Domain	IPR013724	GIT, Spa2 homology (SHD) domain
Domain	IPR022018	ARF GTPase-activating protein GIT1, C-terminal
Domain	IPR032352	Arf GTPase-activating protein GIT1/2, coiled-coil domain
Family	IPR047161	ARF GTPase-activating protein Git-like
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Homologous_superfamily	IPR037278	ARFGAP/RecO-like zinc finger
Homologous_superfamily	IPR038508	ArfGAP domain superfamily
Repeat	IPR002110	Ankyrin repeat

Domain Details Per Protein

Protein	Length	Ankyrin repeat	Ankyrin repeat-containing domain superfamily	ArfGAP domain superfamily	ARFGAP/RecO-like zinc finger	Arf GTPase activating protein	Arf GTPase-activating protein GIT1/2, coiled-coil domain	ARF GTPase-activating protein GIT1, C-terminal	ARF GTPase-activating protein Git-like	GIT, Spa2 homology (SHD) domain
UniProtKB:A0A8M2B2B2 InterPro	738
UniProtKB:A0A8M2B1P7 InterPro	706
UniProtKB:A0A8M2B236 InterPro	708
UniProtKB:A1L1V5 InterPro	736

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	git2b-201 (1) Ensembl	Ensembl	5,480 nt	Select Tool ZFIN BLAST
mRNA	git2b-202 (1) Ensembl	Ensembl	5,871 nt	Select Tool
mRNA	git2b-203 (1) Ensembl	Ensembl	5,481 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations