Gene
trpm4b.1
- ID
- ZDB-GENE-061214-3
- Name
- transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 1
- Symbol
- trpm4b.1 Nomenclature History
- Previous Names
-
- trpm4b2 (1)
- trpm4b
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable calcium activated cation channel activity. Predicted to act upstream of or within several processes, including cardiac conduction; regulation of T cell cytokine production; and vasoconstriction. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 6 and progressive familial heart block type IB. Orthologous to human TRPM4 (transient receptor potential cation channel subfamily M member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| erythrokeratodermia variabilis et progressiva 6 | Alliance | Erythrokeratodermia variabilis et progressiva 6 | 618531 |
| progressive familial heart block type IB | Alliance | Progressive familial heart block, type IB | 604559 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ion transport domain | Transient receptor potential cation channel M | TRPM, SLOG domain |
|---|---|---|---|---|
|
UniProtKB:A0A8M3AY04
|
1226 | |||
|
UniProtKB:A0A8M3B774
|
1225 | |||
|
UniProtKB:A0A8M9QIY9
|
1222 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available