Gene

trpm4b.2

ID
ZDB-GENE-061214-2
Name
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
Symbol
trpm4b.2 Nomenclature History
Previous Names
  • trpm4b1 (1)
  • trpm4c
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have calcium activated cation channel activity. Predicted to be involved in several processes, including cardiac conduction; regulation of T cell cytokine production; and vasoconstriction. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and progressive familial heart block type IB. Orthologous to human TRPM4 (transient receptor potential cation channel subfamily M member 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trpm4b.2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
erythrokeratodermia variabilis et progressiva 6 Alliance Erythrokeratodermia variabilis et progressiva 6 618531
progressive familial heart block type IB Alliance Progressive familial heart block, type IB 604559
Associated With trpm4b.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005821 Ion transport domain
Domain IPR041491 TRPM, SLOG domain
Family IPR050927 Transient receptor potential cation channel M
Domain Details Per Protein
Protein Length Ion transport domain Transient receptor potential cation channel M TRPM, SLOG domain
UniProtKB:F1RC25 1222
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations