Gene
fndc5a
- ID
- ZDB-GENE-061207-40
- Name
- fibronectin type III domain containing 5a
- Symbol
- fndc5a Nomenclature History
- Previous Names
-
- si:ch211-62a1.2
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to be located in membrane. Predicted to be active in extracellular region and plasma membrane. Orthologous to human FNDC5 (fibronectin type III domain containing 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa10564 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR032073 | Fibronectin type III domain-containing protein 5, C-terminal domain |
| Family | IPR052120 | Fibronectin type III domain-containing protein 4/5 |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Fibronectin type III | Fibronectin type III domain-containing protein 4/5 | Fibronectin type III domain-containing protein 5, C-terminal domain | Fibronectin type III superfamily | Immunoglobulin-like fold |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1Q740 | InterPro | 204 | |||||
| UniProtKB:A0AB32TJV5 | InterPro | 222 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fndc5a-201
(1)
|
Ensembl | 534 nt | ||
| mRNA |
fndc5a-202
(1)
|
Ensembl | 1,119 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-62A1 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068213112 (1) | 7410 nt | ||
| Genomic | GenBank:BX914200 (1) | 170183 nt | ||
| Polypeptide | UniProtKB:A0AB32TJV5 (1) | 222 aa |
- Tonelotto, V., Trapani, V., Bretaud, S., Heumüller, S.E., Wagener, R., Ruggiero, F., Bonaldo, P. (2019) Spatio-temporal expression and distribution of collagen VI during zebrafish development. Scientific Reports. 9:19851
- Wang, S., Yang, Q., Wang, Z., Feng, S., Li, H., Ji, D., Zhang, S. (2018) Evolutionary and Expression Analyses Show Co-option of khdrbs Genes for Origin of Vertebrate Brain.. Frontiers in genetics. 8:225
- Sundarrajan, L., Unniappan, S. (2017) Small Interfering RNA Mediated Knockdown of Irisin Suppresses Food Intake and Modulates Appetite Regulatory Peptides in Zebrafish. General and comparative endocrinology. 252:200-208
- Li, X., Fang, W., Hu, Y., Wang, Y., Li, J. (2015) Characterization of fibronectin type III domain-containing protein 5 (FNDC5) gene in chickens: cloning, tissue expression, and regulation of its expression in the muscle by fasting and cold exposure. Gene. 570(2):221-9
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