Gene

cd209

ID
ZDB-GENE-061207-22
Name
CD209 molecule
Symbol
cd209 Nomenclature History
Previous Names
  • DC-SIGN (1)
  • si:ch211-214k5.1
  • si:ch211-224h1.3
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have carbohydrate binding activity. Involved in T cell activation involved in immune response; adaptive immune response; and dendritic cell antigen processing and presentation. Localizes to cell surface. Human ortholog(s) of this gene implicated in Coronavirus infection; aspergillosis; dengue disease; human immunodeficiency virus infectious disease; and tuberculosis. Is expressed in several structures, including heart; immune system; integument; liver; and pleuroperitoneal region. Orthologous to several human genes including CLEC6A (C-type lectin domain containing 6A); CLEC4A (C-type lectin domain family 4 member A); and CLEC4C (C-type lectin domain family 4 member C).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cd209 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Dengue fever, protection against} 614371
{HIV type 1, susceptibility to} 609423
{Mycobacterium tuberculosis, susceptibility to} 607948
Associated With cd209 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018378 C-type lectin, conserved site
Domain IPR001304 C-type lectin-like
Domain IPR033989 CD209-like, C-type lectin-like domain
Homologous_superfamily IPR016186 C-type lectin-like/link domain superfamily
Homologous_superfamily IPR016187 C-type lectin fold
Domain Details Per Protein
Protein Length CD209-like, C-type lectin-like domain C-type lectin, conserved site C-type lectin fold C-type lectin-like C-type lectin-like/link domain superfamily
UniProtKB:F1QW96 343
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA cd209-201 (1) Havana 1420 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cd209 IgG Rabbit
  • IHC
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations