Gene
rbl2
- ID
- ZDB-GENE-061109-2
- Name
- retinoblastoma-like 2 (p130)
- Symbol
- rbl2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have RNA polymerase II activating transcription factor binding activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and negative regulation of G1/S transition of mitotic cell cycle. Predicted to localize to chromatin and transcription regulator complex. Is expressed in neuromast. Orthologous to human RBL2 (RB transcriptional corepressor like 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Brunet-Wagner neurodevelopmental syndrome | 619690 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR002719 | Retinoblastoma-associated protein, B-box |
Domain | IPR002720 | Retinoblastoma-associated protein, A-box |
Domain | IPR013763 | Cyclin-like domain |
Domain | IPR015030 | Retinoblastoma-associated protein, C-terminal |
Domain | IPR024599 | Retinoblastoma-associated protein, N-terminal |
Family | IPR028309 | Retinoblastoma protein family |
Homologous_superfamily | IPR036915 | Cyclin-like superfamily |
Domain Details Per Protein
Protein | Length | Cyclin-like domain | Cyclin-like superfamily | Retinoblastoma-associated protein, A-box | Retinoblastoma-associated protein, B-box | Retinoblastoma-associated protein, C-terminal | Retinoblastoma-associated protein, N-terminal | Retinoblastoma protein family |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M2BA88
|
897 | |||||||
UniProtKB:A0A8M3AZW2
|
1078 | |||||||
UniProtKB:E7FDM3
|
1079 |
Interactions and Pathways
No data available
Plasmids
No data available