Gene

uggt1

ID

ZDB-GENE-061103-619

Name

UDP-glucose glycoprotein glucosyltransferase 1

Symbol

uggt1 Nomenclature History

Previous Names

zgc:152896

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Predicted to be involved in ER-associated misfolded protein catabolic process and protein N-linked glycosylation via asparagine. Predicted to act upstream of or within protein glycosylation. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum. Orthologous to human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7146988 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With uggt1 Human Ortholog

No data available

Associated With uggt1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040497	Glucosyltransferase 24, catalytic domain
Domain	IPR040525	UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4
Domain	IPR040692	UGGT, thioredoxin-like domain 3
Domain	IPR040693	UGGT, thioredoxin-like domain 1
Domain	IPR040694	UGGT, thioredoxin-like domain 2
Family	IPR009448	UDP-glucose:Glycoprotein Glucosyltransferase
Homologous_superfamily	IPR029044	Nucleotide-diphospho-sugar transferases

Domain Details Per Protein

Protein	Length	Glucosyltransferase 24, catalytic domain	Nucleotide-diphospho-sugar transferases	UDP-glucose:Glycoprotein Glucosyltransferase	UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4	UGGT, thioredoxin-like domain 1	UGGT, thioredoxin-like domain 2	UGGT, thioredoxin-like domain 3
UniProtKB:A0JMD3 InterPro	1525
UniProtKB:A0A8M9QEQ5 InterPro	1562
UniProtKB:A0A8M9Q922 InterPro	1554

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	uggt1-201 (1) Ensembl	Ensembl	7,403 nt	Select Tool ZFIN BLAST
mRNA	uggt1-202 (1) Ensembl	Ensembl	7,333 nt	Select Tool ZFIN BLAST
mRNA	uggt1-203 (1) Ensembl	Ensembl	4,853 nt	Select Tool ZFIN BLAST
mRNA	uggt1-204 (1) Ensembl	Ensembl	7,417 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations