Gene
agpat2
- ID
- ZDB-GENE-061103-541
- Name
- 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
- Symbol
- agpat2 Nomenclature History
- Previous Names
-
- zgc:153984
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable 1-acylglycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in phosphatidic acid biosynthetic process. Predicted to act upstream of or within phospholipid biosynthetic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in intestine. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 1 and lipodystrophy. Orthologous to several human genes including AGPAT1 (1-acylglycerol-3-phosphate O-acyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Zhao et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital generalized lipodystrophy type 1 | Alliance | Lipodystrophy, congenital generalized, type 1 | 608594 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 1-acyl-sn-glycerol-3-phosphate acyltransferase | Phospholipid/glycerol acyltransferase |
|---|---|---|---|
|
UniProtKB:A0JMM2
|
271 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
agpat2-201
(1)
|
Ensembl | 3,275 nt |
Interactions and Pathways
No data available
Plasmids
No data available