Gene

pkn2b

ID
ZDB-GENE-061013-393
Name
protein kinase N2b
Symbol
pkn2b Nomenclature History
Previous Names
  • zgc:153916
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to localize to several cellular components, including cleavage furrow; lamellipodium; and midbody. Orthologous to human PKN2 (protein kinase N2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pkn2b Human Ortholog
No data available
Associated With pkn2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000008 C2 domain
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR011072 HR1 rho-binding domain
Domain IPR017892 Protein kinase, C-terminal
Domain IPR037313 Serine/threonine-protein kinase N, first HR1 domain
Domain IPR037784 Serine/threonine-protein kinase N, C2 domain
Family IPR050236 Serine/threonine-protein kinases, AGC
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Homologous_superfamily IPR036274 HR1 repeat superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal C2 domain C2 domain superfamily HR1 repeat superfamily HR1 rho-binding domain Protein kinase, ATP binding site Protein kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine/threonine-protein kinase N, C2 domain Serine/threonine-protein kinase N, first HR1 domain Serine/threonine-protein kinases, AGC
UniProtKB:A7MBL8 977
UniProtKB:A0A2R8RL78 984
UniProtKB:Q08BD6 339
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ottdart00000054614 (1) Ensembl 3,950 nt
mRNA pkn2-201 (1) Ensembl 6,557 nt
mRNA pkn2-203 (1) Ensembl 6,393 nt
mRNA pkn2-204 (1) Ensembl 1,937 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations