Gene
plxna1b
- ID
- ZDB-GENE-061007-1
- Name
- plexin A1b
- Symbol
- plxna1b Nomenclature History
- Previous Names
-
- plxna1
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable semaphorin receptor activity. Acts upstream of or within sprouting angiogenesis and wound healing. Predicted to be located in plasma membrane. Is expressed in several structures, including nervous system; optic vesicle; otic vesicle; presumptive neural retina; and spinal cord neural tube. Orthologous to human PLXNA1 (plexin A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Dworschak-Punetha neurodevelopmental syndrome | 619955 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001627 | Sema domain |
| Domain | IPR002909 | IPT domain |
| Domain | IPR013548 | Plexin, cytoplasmic RasGAP domain |
| Domain | IPR016201 | PSI domain |
| Domain | IPR041019 | Plexin, TIG domain 1 |
| Domain | IPR041362 | Plexin, TIG domain 2 |
| Domain | IPR042744 | Plexin-A1, Sema domain |
| Domain | IPR046800 | Plexin, cytoplasmic RhoGTPase-binding domain |
| Family | IPR031148 | Plexin family |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036352 | Sema domain superfamily |
| Repeat | IPR002165 | Plexin repeat |
Domain Details Per Protein
| Protein | Length | Immunoglobulin E-set | Immunoglobulin-like fold | IPT domain | Plexin-A1, Sema domain | Plexin, cytoplasmic RasGAP domain | Plexin, cytoplasmic RhoGTPase-binding domain | Plexin family | Plexin repeat | Plexin, TIG domain 1 | Plexin, TIG domain 2 | PSI domain | Rho GTPase activation protein | Sema domain | Sema domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A8IYK2
|
1885 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
plxna1-201
(1)
|
Ensembl | 5,658 nt |
Interactions and Pathways
No data available
Plasmids
No data available