Gene
tyw1
- ID
- ZDB-GENE-060929-688
- Name
- tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
- Symbol
- tyw1 Nomenclature History
- Previous Names
-
- im:6898509
- wu:fb74d01
- zgc:153368
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have several functions, including 4 iron, 4 sulfur cluster binding activity; FMN binding activity; and tRNA-4-demethylwyosine synthase activity. Predicted to be involved in oxidation-reduction process and tRNA processing. Predicted to localize to integral component of membrane. Orthologous to several human genes including TYW1 (tRNA-yW synthesizing protein 1 homolog).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6898509 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001094 | Flavodoxin-like |
| Domain | IPR007197 | Radical SAM |
| Domain | IPR008254 | Flavodoxin/nitric oxide synthase |
| Domain | IPR013917 | tRNA wybutosine-synthesis |
| Family | IPR034556 | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase |
| Homologous_superfamily | IPR013785 | Aldolase-type TIM barrel |
| Homologous_superfamily | IPR029039 | Flavoprotein-like superfamily |
Domain Details Per Protein
| Protein | Length | Aldolase-type TIM barrel | Flavodoxin-like | Flavodoxin/nitric oxide synthase | Flavoprotein-like superfamily | Radical SAM | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase | tRNA wybutosine-synthesis |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q08C92
|
730 | |||||||
|
UniProtKB:A0A8M6Z1B5
|
753 |
Interactions and Pathways
No data available
Plasmids
No data available