Gene

oxct1b

ID

ZDB-GENE-060929-212

Name

3-oxoacid CoA transferase 1b

Symbol

oxct1b Nomenclature History

Previous Names

wu:fb66a01
zgc:153275

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable succinyl-CoA:3-oxo-acid CoA-transferase activity. Predicted to be involved in cellular ketone body metabolic process. Predicted to act upstream of or within ketone body catabolic process. Predicted to be active in mitochondrion. Is expressed in liver and yolk syncytial layer. Orthologous to several human genes including OXCT1 (3-oxoacid CoA-transferase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

19 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7156121 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With oxct1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Succinyl CoA:3-oxoacid CoA transferase deficiency	245050

Associated With oxct1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR004164	Coenzyme A transferase active site
Binding_site	IPR004163	Coenzyme A transferase binding site
Domain	IPR012791	3-oxoacid CoA-transferase, subunit B
Domain	IPR012792	3-oxoacid CoA-transferase, subunit A
Family	IPR004165	Coenzyme A transferase family I
Family	IPR014388	3-oxoacid CoA-transferase
Homologous_superfamily	IPR037171	NagB/RpiA transferase-like