Gene
fdx2
- ID
- ZDB-GENE-060929-1046
- Name
- ferredoxin 2
- Symbol
- fdx2 Nomenclature History
- Previous Names
-
- fdx1l
- zgc:153554
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable 2 iron, 2 sulfur cluster binding activity; electron transfer activity; and metal ion binding activity. Predicted to be involved in positive regulation of oxidoreductase activity. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial myopathy. Orthologous to human FDX2 (ferredoxin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial myopathy | Alliance | Mitochondrial myopathy, episodic, with optic atrophy and reversible leukoencephalopathy | 251900 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018298 | Adrenodoxin, iron-sulphur binding site |
| Domain | IPR001041 | 2Fe-2S ferredoxin-type iron-sulfur binding domain |
| Family | IPR001055 | Adrenodoxin-like |
| Homologous_superfamily | IPR012675 | Beta-grasp domain superfamily |
| Homologous_superfamily | IPR036010 | 2Fe-2S ferredoxin-like superfamily |
Domain Details Per Protein
| Protein | Length | 2Fe-2S ferredoxin-like superfamily | 2Fe-2S ferredoxin-type iron-sulfur binding domain | Adrenodoxin, iron-sulphur binding site | Adrenodoxin-like | Beta-grasp domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q08C57
|
195 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available