Gene
cln8
- ID
- ZDB-GENE-060906-3
- Name
- CLN8 transmembrane ER and ERGIC protein
- Symbol
- cln8 Nomenclature History
- Previous Names
-
- zgc:172202
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 8 and neuronal ceroid lipofuscinosis 8 northern epilepsy variant. Orthologous to human CLN8 (CLN8 transmembrane ER and ERGIC protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neuronal ceroid lipofuscinosis 8 | Alliance | Ceroid lipofuscinosis, neuronal, 8 | 600143 |
| neuronal ceroid lipofuscinosis 8 northern epilepsy variant | Alliance | Ceroid lipofuscinosis, neuronal, 8, Northern epilepsy variant | 610003 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | TLC domain-containing | TRAM/LAG1/CLN8 homology domain |
|---|---|---|---|
|
UniProtKB:F1QYC0
|
289 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| antisense |
ottdart00000059933
(1)
|
Ensembl | 1,026 nt | ||
| antisense |
ottdart00000059935
(1)
|
Ensembl | 461 nt | ||
| mRNA |
cln8-201
(1)
|
Ensembl | 1,713 nt | ||
| mRNA |
cln8-203
(1)
|
Ensembl | 1,490 nt | ||
| ncRNA |
cln8-002
(1)
|
Ensembl | 532 nt |
Interactions and Pathways
No data available
Plasmids
No data available