Gene
frmd7
- ID
- ZDB-GENE-060825-67
- Name
- FERM domain containing 7
- Symbol
- frmd7 Nomenclature History
- Previous Names
-
- zgc:153674
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have cytoskeletal protein binding activity. Predicted to localize to cytoskeleton and integral component of membrane. Human ortholog(s) of this gene implicated in congenital nystagmus. Orthologous to human FRMD7 (FERM domain containing 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital nystagmus 1 | Alliance | Nystagmus 1, congenital, X-linked | 310700 |
| congenital nystagmus 1 | Alliance | Nystagmus, infantile periodic alternating, X-linked | 310700 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019747 | FERM conserved site |
| Domain | IPR000299 | FERM domain |
| Domain | IPR014847 | FERM adjacent |
| Domain | IPR018979 | FERM, N-terminal |
| Domain | IPR018980 | FERM, C-terminal PH-like domain |
| Domain | IPR019748 | FERM central domain |
| Domain | IPR019749 | Band 4.1 domain |
| Domain | IPR041788 | FARP1/FARP2/FRMD7, FERM domain C-lobe |
| Family | IPR000798 | Ezrin/radixin/moesin-like |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR014352 | FERM/acyl-CoA-binding protein superfamily |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR035963 | FERM superfamily, second domain |
Domain Details Per Protein
| Protein | Length | Band 4.1 domain | Ezrin/radixin/moesin-like | FARP1/FARP2/FRMD7, FERM domain C-lobe | FERM/acyl-CoA-binding protein superfamily | FERM adjacent | FERM central domain | FERM conserved site | FERM, C-terminal PH-like domain | FERM domain | FERM, N-terminal | FERM superfamily, second domain | PH-like domain superfamily | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PCT6
|
300 | |||||||||||||
|
UniProtKB:A0A8M2BL62
|
722 | |||||||||||||
|
UniProtKB:F1R8Z1
|
253 | |||||||||||||
|
UniProtKB:A0A8M9PQL4
|
497 |
Interactions and Pathways
No data available
Plasmids
No data available