Gene

exd1

ID

ZDB-GENE-060825-267

Name

exonuclease 3'-5' domain containing 1

Symbol

exd1 Nomenclature History

Previous Names

zgc:154068 (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have RNA binding activity and protein homodimerization activity. Predicted to be involved in gene silencing by RNA and piRNA metabolic process. Predicted to localize to P granule and PET complex. Is expressed in hindbrain neural keel; midbrain hindbrain boundary; midbrain neural rod; neural plate; and rhombomere. Orthologous to human EXD1 (exonuclease 3'-5' domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7147862 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With exd1 Human Ortholog

No data available

Associated With exd1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002562	3'-5' exonuclease domain
Family	IPR052144	piRNA biogenesis EXD1-related protein
Homologous_superfamily	IPR012337	Ribonuclease H-like superfamily
Homologous_superfamily	IPR036397	Ribonuclease H superfamily