Gene

chst6

ID

ZDB-GENE-060810-74

Name

carbohydrate sulfotransferase 6

Symbol

chst6 Nomenclature History

Previous Names

im:7157221 (1)
zgc:194879 (1)

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and sulfur compound metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in macular corneal dystrophy. Orthologous to human CHST5 (carbohydrate sulfotransferase 5) and CHST6 (carbohydrate sulfotransferase 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7157221 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With chst6 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
macular corneal dystrophy	Alliance	Macular corneal dystrophy	217800

Associated With chst6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000863	Sulfotransferase domain
Family	IPR016469	Carbohydrate sulfotransferase
Family	IPR051135	Gal/GlcNAc/GalNAc Sulfotransferase
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase