Gene

amn

ID
ZDB-GENE-060810-59
Name
amnion associated transmembrane protein
Symbol
amn Nomenclature History
Previous Names
  • im:7155895
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to be involved in protein localization and receptor-mediated endocytosis. Predicted to act upstream of or within protein transport. Predicted to be located in plasma membrane. Predicted to be active in apical plasma membrane and endocytic vesicle. Is expressed in lysosome-rich enterocyte and pronephros. Human ortholog(s) of this gene implicated in megaloblastic anemia. Orthologous to human AMN (amnion associated transmembrane protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Park et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
pd1189Allele with one deletionExon 1Frameshift, Premature StopCRISPR
sa6923Allele with one point mutationUnknownPremature StopENU
1 - 2 of 2
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-amnPark et al., 2019
1 - 1 of 1
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Human Disease
Associated With amn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Imerslund-Grasbeck syndrome 2 618882
1 - 1 of 1
Associated With amn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR026112 Amnionless
1 - 1 of 1
Domain Details Per Protein
Protein Length Amnionless
UniProtKB:A0A8M9QAN8 538
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 3
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA amn-201 (1) Ensembl 1,639 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-194O9ZFIN Curated Data
EncodesESTIMAGE:7155895Thisse et al., 2004
1 - 2 of 2
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanAMN14
Amino acid sequence comparison (1)
MouseAmn12
Amino acid sequence comparison (1)
Citations