ZFIN is now using GRCz12tu for Genomic Data
Gene
mdc1
- ID
- ZDB-GENE-060810-185
- Name
- mediator of DNA damage checkpoint 1
- Symbol
- mdc1 Nomenclature History
- Previous Names
-
- im:7163673 (1)
- sb:eu278
- si:ch73-309n4.5
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable histone reader activity. Predicted to be involved in DNA damage response and DNA replication checkpoint signaling. Predicted to be located in chromosome. Predicted to be active in nucleus and site of double-strand break. Orthologous to human MDC1 (mediator of DNA damage checkpoint 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | BRCT domain | BRCT domain superfamily | DNA Damage Response and Transcriptional Regulator | Forkhead-associated (FHA) domain | SMAD/FHA domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8N7T6W3 | InterPro | 1914 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance