Gene

fbln2

ID

ZDB-GENE-060711-1

Name

fibulin 2

Symbol

fbln2 Nomenclature History

Previous Names

im:6907068

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity. Predicted to be involved in extracellular matrix organization. Predicted to localize to collagen-containing extracellular matrix. Is expressed in several structures, including cardiovascular system; hypochord; intestinal bulb; mesoderm; and tail bud. Orthologous to human FBLN2 (fibulin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6907068 (21 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fbln2 Human Ortholog

No data available

Associated With fbln2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Domain	IPR000020	Anaphylatoxin/fibulin
Domain	IPR000742	EGF-like domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR026823	Complement Clr-like EGF domain
Domain	IPR049883	NOTCH1 EGF-like calcium-binding domain
Family	IPR050751	Extracellular matrix structural protein
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
PTM	IPR000152	EGF-type aspartate/asparagine hydroxylation site

Domain Details Per Protein

Protein	Length	Anaphylatoxin/fibulin	Complement Clr-like EGF domain	EGF-like calcium-binding, conserved site	EGF-like calcium-binding domain	EGF-like domain	EGF-type aspartate/asparagine hydroxylation site	Extracellular matrix structural protein	Growth factor receptor cysteine-rich domain superfamily	NOTCH1 EGF-like calcium-binding domain
UniProtKB:F1RCR3 InterPro	1408
UniProtKB:A0A8M2BH82 InterPro	1361

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fbln2-201 (1) Ensembl	Ensembl	5,443 nt	Select Tool ZFIN BLAST
mRNA	fbln2-203 (1) Ensembl	Ensembl	661 nt	Select Tool ZFIN BLAST
mRNA	fbln2-204 (1) Ensembl	Ensembl	912 nt	Select Tool ZFIN BLAST
mRNA	fbln2-205 (1) Ensembl	Ensembl	1,224 nt	Select Tool ZFIN BLAST
ncRNA	fbln2-003 (1) Ensembl	Ensembl	504 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations