Gene
f2r
- ID
- ZDB-GENE-060526-30
- Name
- coagulation factor II (thrombin) receptor
- Symbol
- f2r Nomenclature History
- Previous Names
-
- PAR1-5A (1)
- si:ch211-130m23.4
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits thrombin-activated receptor activity. Involved in cardiovascular system development; endothelial to hematopoietic transition; and negative regulation of hematopoietic stem cell differentiation. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; digestive system; intermediate cell mass of mesoderm; mesoderm; and pleuroperitoneal region. Orthologous to human F2R (coagulation factor II thrombin receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Protease-activated receptor | Thrombin receptor |
|---|---|---|---|---|---|
|
UniProtKB:A2BIP6
|
413 |
Interactions and Pathways
No data available
Plasmids
No data available