Gene
si:ch211-114c12.5
- ID
- ZDB-GENE-060526-13
- Name
- si:ch211-114c12.5
- Symbol
- si:ch211-114c12.5 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including IgA vasculitis; Sweet syndrome; asthma; familial Mediterranean fever; and hematologic cancer (multiple). Orthologous to human MEFV (MEFV innate immunity regulator, pyrin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001870 | B30.2/SPRY domain |
| Domain | IPR003877 | SPRY domain |
| Domain | IPR003879 | Butyrophylin-like, SPRY domain |
| Domain | IPR006574 | SPRY-associated |
| Family | IPR050143 | Tripartite motif-containing |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR043136 | B30.2/SPRY domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | B30.2/SPRY domain | B30.2/SPRY domain superfamily | Butyrophylin-like, SPRY domain | Concanavalin A-like lectin/glucanase domain superfamily | SPRY-associated | SPRY domain | Tripartite motif-containing |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PKM7 | InterPro | 419 | |||||||
| UniProtKB:A0A8M9P8U7 | InterPro | 346 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-114c12.5-201
(1)
|
Ensembl | 1,376 nt |
Interactions and Pathways
No data available
Plasmids
No data available