Gene

gcat

ID

ZDB-GENE-060518-3

Name

glycine C-acetyltransferase

Symbol

gcat Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to enable glycine C-acetyltransferase activity and pyridoxal phosphate binding activity. Predicted to act upstream of or within biosynthetic process and threonine catabolic process. Predicted to be active in mitochondrion. Orthologous to human GCAT (glycine C-acetyltransferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Kizil et al., 2022

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gcat Human Ortholog

No data available

Associated With gcat Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR001917	Aminotransferase, class-II, pyridoxal-phosphate binding site
Domain	IPR004839	Aminotransferase, class I/classII, large domain
Family	IPR011282	2-amino-3-ketobutyrate coenzyme A ligase
Family	IPR050087	8-amino-7-oxononanoate synthase class-II
Homologous_superfamily	IPR015421	Pyridoxal phosphate-dependent transferase, major domain
Homologous_superfamily	IPR015422	Pyridoxal phosphate-dependent transferase, small domain
Homologous_superfamily	IPR015424	Pyridoxal phosphate-dependent transferase