Gene

tle2c

ID
ZDB-GENE-060512-84
Name
TLE family member 2, transcriptional corepressor c
Symbol
tle2c Nomenclature History
Previous Names
  • zgc:136336 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have repressing transcription factor binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to localize to nucleus and transcription factor complex. Orthologous to human TLE2 (TLE family member 2, transcriptional corepressor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Thyme et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tle2c Human Ortholog
No data available
Associated With tle2c Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005617 Groucho/TLE, N-terminal Q-rich domain
Family IPR009146 Groucho/transducin-like enhancer
Domain Details Per Protein
Protein Length Groucho/TLE, N-terminal Q-rich domain Groucho/transducin-like enhancer
UniProtKB:Q1JQ32 341
UniProtKB:A0A8M3B7Z7 353
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations