Gene
chrna10a
- ID
- ZDB-GENE-060503-725
- Name
- cholinergic receptor, nicotinic, alpha 10a
- Symbol
- chrna10a Nomenclature History
- Previous Names
-
- chrna10
- si:dkey-24p1.3
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have acetylcholine-gated cation-selective channel activity and transmembrane signaling receptor activity. Predicted to be involved in several processes, including chemical synaptic transmission; nervous system process; and regulation of membrane potential. Predicted to localize to integral component of plasma membrane; neuron projection; and synapse. Orthologous to human CHRNA10 (cholinergic receptor nicotinic alpha 10 subunit) and CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018000 | Neurotransmitter-gated ion-channel, conserved site |
| Domain | IPR006029 | Neurotransmitter-gated ion-channel transmembrane domain |
| Domain | IPR006202 | Neurotransmitter-gated ion-channel ligand-binding domain |
| Family | IPR002394 | Nicotinic acetylcholine receptor |
| Family | IPR006201 | Neurotransmitter-gated ion-channel |
| Homologous_superfamily | IPR036719 | Neurotransmitter-gated ion-channel transmembrane domain superfamily |
| Homologous_superfamily | IPR036734 | Neurotransmitter-gated ion-channel ligand-binding domain superfamily |
| Homologous_superfamily | IPR038050 | Neuronal acetylcholine receptor |
Domain Details Per Protein
| Protein | Length | Neuronal acetylcholine receptor | Neurotransmitter-gated ion-channel | Neurotransmitter-gated ion-channel, conserved site | Neurotransmitter-gated ion-channel ligand-binding domain | Neurotransmitter-gated ion-channel ligand-binding domain superfamily | Neurotransmitter-gated ion-channel transmembrane domain | Neurotransmitter-gated ion-channel transmembrane domain superfamily | Nicotinic acetylcholine receptor |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:R4GF05
|
532 | ||||||||
|
UniProtKB:Q1LY90
|
527 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
chrna10a-201
(1)
|
Ensembl | 1,584 nt | ||
| mRNA |
chrna10a-202
(1)
|
Ensembl | 1,846 nt |
Interactions and Pathways
No data available
Plasmids
No data available