Gene
irak3
- ID
- ZDB-GENE-060503-710
- Name
- interleukin-1 receptor-associated kinase 3
- Symbol
- irak3 Nomenclature History
- Previous Names
-
- si:dkey-150i15.2
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Involved in embryonic hemopoiesis. Predicted to localize to cytoplasm; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IRAK3 (interleukin 1 receptor associated kinase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Stockhammer et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Eckfeldt et al., 2005
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Asthma susceptibility 5} | 611064 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Death domain | Death-like domain superfamily | IRAK3, death domain | Protein kinase domain | Protein kinase-like domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:B0UYS2
|
630 |
Interactions and Pathways
No data available
Plasmids
No data available