Gene
baiap2a
- ID
- ZDB-GENE-060421-2756
- Name
- BAR/IMD domain containing adaptor protein 2a
- Symbol
- baiap2a Nomenclature History
- Previous Names
-
- wu:fk29g02
- zgc:136827
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable cytoskeletal anchor activity. Predicted to be involved in actin crosslink formation; actin filament bundle assembly; and positive regulation of actin filament polymerization. Predicted to act upstream of or within plasma membrane organization and regulation of actin cytoskeleton organization. Predicted to be located in several cellular components, including cytoskeleton; filopodium; and ruffle. Predicted to be active in cytosol and nucleoplasm. Is expressed in dorsal telencephalon. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and autism spectrum disorder. Orthologous to human BAIAP2 (BAR/IMD domain containing adaptor protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR013606 | IMD/I-BAR domain |
| Domain | IPR030128 | BAR/IMD domain-containing adapter protein 2, I-BAR domain |
| Domain | IPR035594 | BAR/IMD domain-containing adapter protein 2, SH3 domain |
| Family | IPR027681 | I-BAR domain containing protein IRSp53/IRTKS/Pinkbar |
| Homologous_superfamily | IPR027267 | AH/BAR domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | BAR/IMD domain-containing adapter protein 2, I-BAR domain | BAR/IMD domain-containing adapter protein 2, SH3 domain | I-BAR domain containing protein IRSp53/IRTKS/Pinkbar | IMD/I-BAR domain | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AQY0
|
485 | |||||||
|
UniProtKB:A0A8M9PQ60
|
536 | |||||||
|
UniProtKB:Q1RLU7
|
506 | |||||||
|
UniProtKB:A0A8M2BAV5
|
549 | |||||||
|
UniProtKB:A0A8M3B8K0
|
465 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
baiap2a-201
(1)
|
Ensembl | 2,698 nt | ||
| mRNA |
baiap2a-202
(1)
|
Ensembl | 3,391 nt | ||
| mRNA |
baiap2a-203
(1)
|
Ensembl | 4,757 nt |
Interactions and Pathways
No data available
Plasmids
No data available