Gene

pou2f2a

ID

ZDB-GENE-060310-2

Name

POU class 2 homeobox 2a

Symbol

pou2f2a Nomenclature History

Previous Names

Oct2a (1)
pou2f2
id:ibd5128
im:7160081
si:dkey-3j24.1

Type

protein_coding_gene

Location

Ambiguous Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in forebrain; immature eye; and midbrain. Orthologous to human POU2F2 (POU class 2 homeobox 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7160081 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pou2f2a Human Ortholog

No data available

Associated With pou2f2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR000327	POU-specific domain
Domain	IPR001356	Homeodomain
Domain	IPR013847	POU domain
Family	IPR000972	Octamer-binding transcription factor
Family	IPR050255	POU domain transcription factor
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR010982	Lambda repressor-like, DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Homedomain-like superfamily	Homeobox, conserved site	Homeodomain	Lambda repressor-like, DNA-binding domain superfamily	Octamer-binding transcription factor	POU domain	POU domain transcription factor	POU-specific domain
UniProtKB:A0A8M3AQD8 InterPro	705
UniProtKB:A0A8M6Z1Z0 InterPro	691
UniProtKB:A0A8M6YVD3 InterPro	702
UniProtKB:A0A8M3AT79 InterPro	712
UniProtKB:A0A8M3B3B2 InterPro	687
UniProtKB:A0A8M6Z1A5 InterPro	601
UniProtKB:A0A8M9P294 InterPro	676
UniProtKB:A0A8M6YSU9 InterPro	691

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	pou2f2a-205 (1) Ensembl	Ensembl		6,150 nt	Select Tool
ncRNA	pou2f2a-002 (1) Ensembl	Ensembl		756 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations